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AuthorTitleYearJournal/ProceedingsReftypeDOI/URL
Kotha, S. and Singh, K. N-Alkylation of diethyl acetamidomalonate: Synthesis of constrained amino acid derivatives by ring-closing metathesis 2004 Tetrahedron Letters
Vol. 45(52), pp. 9607-9610 
article DOI URL 
Abstract: An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs 2CO 3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields. An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs 2CO 3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields. textcopyright 2004 Published by Elsevier Ltd.
BibTeX:
@article{Kotha2004,
  author = {Kotha, Sambasivarao and Singh, Kuldeep},
  title = {N-Alkylation of diethyl acetamidomalonate: Synthesis of constrained amino acid derivatives by ring-closing metathesis},
  journal = {Tetrahedron Letters},
  publisher = {Elsevier},
  year = {2004},
  volume = {45},
  number = {52},
  pages = {9607--9610},
  url = {https://linkinghub.elsevier.com/retrieve/pii/S0040403904024487},
  doi = {https://doi.org/10.1016/j.tetlet.2004.11.013}
}
Thallapally, P.K., Jetti, R.K.R., Katz, A.K., Carrell, H.L., Singh, K., Lahiri, K., Kotha, S., Boese, R. and Desiraju, G.R. Polymorphism of 1,3,5-Trinitrobenzene Induced by a Trisindane Additive 2004 Angewandte Chemie International Edition
Vol. 43(9), pp. 1149-1155 
article DOI URL 
Abstract: The most stable is not necessarily the most easy to obtain! Two new stable crystal forms of the 120 year old compound sym-trinitrobenzene are reported. These elusive forms have been obtained by the use of an additive, trisindane, that can act as a mimic in the crystallization experiment (see scheme).
BibTeX:
@article{pop00001,
  author = {Thallapally, Praveen K. and Jetti, Ram K. R. and Katz, Amy K. and Carrell, H. L. and Singh, Kuldeep and Lahiri, Kakali and Kotha, Sambasivarao and Boese, Roland and Desiraju, Gautam R.},
  title = {Polymorphism of 1,3,5-Trinitrobenzene Induced by a Trisindane Additive},
  journal = {Angewandte Chemie International Edition},
  year = {2004},
  volume = {43},
  number = {9},
  pages = {1149--1155},
  url = {http://doi.wiley.com/10.1002/anie.200352253},
  doi = {https://doi.org/10.1002/anie.200352253}
}
Halve, A.K., Dubey, R., Bhadauria, D., Bhaskar, B. and Bhadauria, R. Synthesis, antimicrobial screening and structure-activity relationship of some novel 2-hydroxy-5-(nitro-substituted phenylazo) benzylidine anilines 2006 Indian Journal of Pharmaceutical Sciences
Vol. 68(4), pp. 510-514 
article DOI  
Abstract: The title compounds were synthesized by the condensation of nitro-substituted 2-hydroxy-5- (nitro-substituted phenylazo) benzaldehyde (3) with different aromatic amines in presence of ethanol in good yield. The chemical structures were confirmed by IR, 1H NMR and elemental analysis. All the synthesized compounds (4a-j) have been evaluated for their in vitro antimicrobial activity against S. aureus , P. aeruginosa , E. coli , A. fumigatus , A. niger and C. neoformans.
BibTeX:
@article{Halve2006,
  author = {Halve, A. K. and Dubey, R. and Bhadauria, D. and Bhaskar, B. and Bhadauria, R.},
  title = {Synthesis, antimicrobial screening and structure-activity relationship of some novel 2-hydroxy-5-(nitro-substituted phenylazo) benzylidine anilines},
  journal = {Indian Journal of Pharmaceutical Sciences},
  year = {2006},
  volume = {68},
  number = {4},
  pages = {510--514},
  doi = {https://doi.org/10.4103/0250-474X.27831}
}
Halve, A.K., Bhaskar, B., Sharma, V., Bhadauria, D. and Bhadauria, R. Facile synthesis and antimicrobial screening of some biorelevant thiosemicarbazone and its analogues 2007 Journal of the Indian Chemical Society
Vol. 84(10), pp. 1032-1034 
article  
Abstract: Few new thiosemicarbazones (2 and 3) have been synthesized by condensing 2-hydroxy-5-(substituted phenyl azo) benzaldehyde 1(i) and p-substituted phenyl thiosemicarbazide 1(ii) in DMSO to enhance its medicinal value. The compounds are reported along with their spectral data, antifungal and antibacterial activities.
BibTeX:
@article{Halve2007,
  author = {Halve, Anand K. and Bhaskar, Bhuwan and Sharma, Vasudha and Bhadauria, Deepti and Bhadauria, Raman},
  title = {Facile synthesis and antimicrobial screening of some biorelevant thiosemicarbazone and its analogues},
  journal = {Journal of the Indian Chemical Society},
  year = {2007},
  volume = {84},
  number = {10},
  pages = {1032--1034}
}
Halve, A.K., Bhadauria, D., Bhaskar, B., Dubey, R. and Bhadauria, R. Design, synthesis and in vitro antibacterial studies of some biologically significant N-3-chloro-4-[2′-hydroxy-5′-(phenylazo)phenyl]azetidin- 2-ones 2007 Journal of the Indian Chemical Society
Vol. 84(2), pp. 193-196 
article DOI  
Abstract: The title compounds 3a-h were prepared via the reaction of imine derivatives viz. substituted 2-hydroxy-5-(4′-nitrophenylazo)benzylidine anilines 2a-h with ketenes generated by the reaction of chloroacetylchloride with triethylamine in 1,4-dioxane. The structures of synthesized compounds were assigned by elemental analysis and IR and 1H NMR spectral datas. All the synthesized azetidin-2-ones 3a-h were assayed for their in vitro antibacterial activity against several Gram-positive and Gram-negative bacterial pathogens. Some of the compounds have shown marginal activity.
BibTeX:
@article{Halve2007a,
  author = {Halve, Anand K. and Bhadauria, Deepti and Bhaskar, Bhuwan and Dubey, Rakesh and Bhadauria, Raman},
  title = {Design, synthesis and in vitro antibacterial studies of some biologically significant N-3-chloro-4-[2′-hydroxy-5′-(phenylazo)phenyl]azetidin- 2-ones},
  journal = {Journal of the Indian Chemical Society},
  year = {2007},
  volume = {84},
  number = {2},
  pages = {193--196},
  doi = {https://doi.org/10.1002/chin.200742095}
}
Kotha, S. and Singh, K. Cross-Enyne and Ring-Closing Metathesis Cascade: A Building-Block Approach Suitable for Diversity-Oriented Synthesis of Densely Functionalized Macroheterocycles with Amino Acid Scaffolds 2007 European Journal of Organic Chemistry
Vol. 2007(35), pp. 5909-5916 
article DOI URL 
Abstract: Suitably functionalized glycine derivatives undergo a cross-enyne and ring-closing metathesis cascade to generate macroheterocyclic ring systems in good yield. These macrocycles, prepared on the basis of a fragment coupling strategy, consist of 13-16-membered rings. To this end, 1,5-hexadiene was found to be a promising cross-coupling partner to generate macrocycles by this tandem metathesis sequence. textcopyright Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
BibTeX:
@article{Kotha2007,
  author = {Kotha, Sambasivarao and Singh, Kuldeep},
  title = {Cross-Enyne and Ring-Closing Metathesis Cascade: A Building-Block Approach Suitable for Diversity-Oriented Synthesis of Densely Functionalized Macroheterocycles with Amino Acid Scaffolds},
  journal = {European Journal of Organic Chemistry},
  year = {2007},
  volume = {2007},
  number = {35},
  pages = {5909--5916},
  url = {http://doi.wiley.com/10.1002/ejoc.200700744},
  doi = {https://doi.org/10.1002/ejoc.200700744}
}
Halve, A.K., Bhashkar, B., Sharma, V., Bhadauria, R., Kankoriya, A., Soni, A. and Tiwari, K. Synthesis and in vitro antimicrobial studies of some new 3-[phenyldiazenyl] benzaldehyde N-phenyl thiosemicarbazones 2008 Journal of Enzyme Inhibition and Medicinal Chemistry
Vol. 23(1), pp. 77-81 
article DOI  
Abstract: The increasing clinical importance of drug resistant microbial pathogens has lent additional urgency to microbiological research and new antimicrobial compound development. For this purpose, a new series of 3-[phenyldiazenyl] benzaldehyde N-phenylthiosemicarbazones were synthesized and evaluated for antifungal and antibacterial activity. The reaction of 2-hydroxy-5-[phenyldiazenyl] benzaldehyde (I) with N-phenylhydrazinecarbothioamide (II) were carried out in DMF. The antimicrobial activity of the synthesized target compounds (III) were evaluated by screening on different human pathogens using the disc diffusion assay. All the compounds exhibited considerable inhibition against the bacteria and fungi tested.
BibTeX:
@article{Halve2008,
  author = {Halve, Anand K. and Bhashkar, Bhuwan and Sharma, Vasudha and Bhadauria, Raman and Kankoriya, Amit and Soni, Ajay and Tiwari, Kiran},
  title = {Synthesis and in vitro antimicrobial studies of some new 3-[phenyldiazenyl] benzaldehyde N-phenyl thiosemicarbazones},
  journal = {Journal of Enzyme Inhibition and Medicinal Chemistry},
  year = {2008},
  volume = {23},
  number = {1},
  pages = {77--81},
  doi = {https://doi.org/10.1080/14756360701408614}
}
Kotha, S., Seema, V., Singh, K. and Deodhar, K.D. Strategic utilization of catalytic metathesis and photo-thermal metathesis in caged polycyclic frames 2010 Tetrahedron Letters
Vol. 51(17), pp. 2301-2304 
article DOI URL 
Abstract: Highly functionalized cage compounds have been prepared via cross-metathesis (CM) using Grubbs modified N-tolyl catalyst 7. A strategic utilization of photo-thermal metathesis and catalytic metathesis sequence for the synthesis of functionalized caged molecules has been demonstrated. textcopyright 2010 Elsevier Ltd. All rights reserved.
BibTeX:
@article{pop00008,
  author = {Kotha, Sambasivarao and Seema, Vittal and Singh, Kuldeep and Deodhar, Kodand Dinkar},
  title = {Strategic utilization of catalytic metathesis and photo-thermal metathesis in caged polycyclic frames},
  journal = {Tetrahedron Letters},
  year = {2010},
  volume = {51},
  number = {17},
  pages = {2301--2304},
  url = {https://linkinghub.elsevier.com/retrieve/pii/S0040403910003424},
  doi = {https://doi.org/10.1016/j.tetlet.2010.02.131}
}
Kotha, S., Bansal, D., Singh, K. and Banerjee, S. Synthesis of a new fluorescent macrocyclic α-amino acid derivative via tandem cross-enyne/ring-closing metathesis cascade catalyzed by ruthenium based catalysts 2011 Journal of Organometallic Chemistry
Vol. 696(9), pp. 1856-1860 
article DOI URL 
Abstract: A simple methodology to a unique macrocyclic α-amino acid (AAA) derivative involving three step synthetic sequence has been reported. In addition, various ruthenium based catalysts were studied to enhance the selectivity of the desired macrocyclic AAA derivative 6. The fluorescence behavior of these AAA derivatives 5 and 6 indicate their potential applications in biological sciences as biomarkers, ion sensors and peptidomimetics. textcopyright 2010 Elsevier B.V. All rights reserved.
BibTeX:
@article{pop00005,
  author = {Kotha, Sambasivarao and Bansal, Deepti and Singh, Kuldeep and Banerjee, Subhasree},
  title = {Synthesis of a new fluorescent macrocyclic α-amino acid derivative via tandem cross-enyne/ring-closing metathesis cascade catalyzed by ruthenium based catalysts},
  journal = {Journal of Organometallic Chemistry},
  year = {2011},
  volume = {696},
  number = {9},
  pages = {1856--1860},
  url = {https://linkinghub.elsevier.com/retrieve/pii/S0022328X1100132X},
  doi = {https://doi.org/10.1016/j.jorganchem.2011.02.019}
}
Chanda, S., Sarethy, I.P., De, B. and Singh, K. Paederia foetida — a promising ethno-medicinal tribal plant of northeastern India 2013 Journal of Forestry Research
Vol. 24(4), pp. 801-808 
article DOI URL 
Abstract: The northeastern region of India constitutes one of the biodiversity hotspots of the world. The ethnic groups inhabiting this region practice their distinctive traditional knowledge systems using biodiversity for food, shelter and healthcare. Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. Many of its therapeutic properties relate to the gastrointestinal system and suggest its potential utility for gastrointestinal ailments. This is a review of the ethnobotanical uses, phytochemistry and therapeutic properties of P. foetida compiled from various reports. P. foetida is promising as a remedy for life-style related conditions, especially treatment of ulcers. Its utility highlights the need for proper evaluation of tribal plants as medicines and the species could be considered for development of new drugs. textcopyright 2013 Northeast Forestry University and Springer-Verlag Berlin Heidelberg.
BibTeX:
@article{pop00006,
  author = {Chanda, Silpi and Sarethy, Indira P. and De, Biplab and Singh, Kuldeep},
  title = {Paederia foetida — a promising ethno-medicinal tribal plant of northeastern India},
  journal = {Journal of Forestry Research},
  year = {2013},
  volume = {24},
  number = {4},
  pages = {801--808},
  url = {http://link.springer.com/10.1007/s11676-013-0369-2},
  doi = {https://doi.org/10.1007/s11676-013-0369-2}
}
Silpi Chanda, Valentina Gehlot, Rajashree Das, Shweta Mahant,K unal Das, Kuldeep Singh, S.A., Chanda, S., Gehlot, V., Das, R., Mahant, S., Das, K., Singh, K. and Ahmad, S. Antimicrobial activity of herbal extract against drug resistant H. pylori isolates from India 2014 World journal of pharmaceutical Research
Vol. 3(4), pp. 1234-1243 
article URL 
Abstract: Treatment failure is a major cause of concern for the Helicobacter pylorirelated gastroduodenal diseases like gastritis, peptic ulcer and gastric cancer. The antibacterial activity of Paederiafoetidaagainst few clinical isolates of H.pyloriin vitro was evaluated. The methanolicleaf extractshowing its effectiveness in inhibiting in vitroH. pylori growth irrespective of the genetic makeup of the strains. This study provides novel insights into the therapeutic effect of P. foetidaagainst H. pylori infection, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of P. foetida.
BibTeX:
@article{pop00012,
  author = {Silpi Chanda, Valentina Gehlot, Rajashree Das, Shweta Mahant,K unal Das, Kuldeep Singh, Sayeed Ahmad and Chanda, S and Gehlot, V and Das, R and Mahant, S and Das, K and Singh, K and Ahmad, S},
  title = {Antimicrobial activity of herbal extract against drug resistant H. pylori isolates from India},
  journal = {World journal of pharmaceutical Research},
  year = {2014},
  volume = {3},
  number = {4},
  pages = {1234--1243},
  url = {http://www.wjpr.net/dashboard/abstractid/1017}
}
Chanda, S., Ahmad, S. and Singh, K. Comparison of in vitro antioxidant potential of fractioned Paederia foetida leaf extract 2014 International Journal of Drug Development and Research
Vol. 6(2), pp. 105-109 
article URL 
Abstract: The aim of this study was to investigate the antioxidant activity of different fractionated extracts of leaves of Paederia foetida by DPPH* scavenging assay and phytochemical analysis of the methanolic extract of the leaf. Materials and Methods: The fresh leaves of P. foetida was extracted by using methanol and then proceed for solvent fractionation. The extract was tested for phytochemical analysis and antioxidant activity using DPPH* scavenging assay. Results: Methanolic extract showed the presence of triterpenoids, volatile oil, sterols, alkaloid and glycoside. The yield of methanolic extract was 36%w/w which showed the highest antioxidant activity as compared to other fractions. Conclusion: Paederia foetida leaf extracts possessed free radical scavenging activity. textcopyright 2014 By IYPF All rights reserved.
BibTeX:
@article{pop00013,
  author = {Chanda, Silpi and Ahmad, Sayeed and Singh, Kuldeep},
  title = {Comparison of in vitro antioxidant potential of fractioned Paederia foetida leaf extract},
  journal = {International Journal of Drug Development and Research},
  year = {2014},
  volume = {6},
  number = {2},
  pages = {105--109},
  url = {https://www.ijddr.in/drug-development/comparison-of-in-vitro-antioxidant-potential-of-fractioned-paederiafoetida-leaf-extract.php?aid=5515}
}
Chanda, S., Deb, L., Tiwari, R.K., Singh, K. and Ahmad, S. Gastroprotective mechanism of Paederia foetida Linn. (Rubiaceae) – a popular edible plant used by the tribal community of North-East India 2015 BMC Complementary and Alternative Medicine
Vol. 15(1), pp. 304 
article DOI URL 
Abstract: Background: The objective of the present study is to evaluate the gastroprotective activity of Paederia foetida L. leaf for gastric ulcer. Methods: The methanol extract of P. foetida L. leaves at two different dose levels was investigated for gastroprotective potential by using Indomethacin-pylorus ligation, alcohol induced and water immersion stress induced model in rats. In vitro DPPH* radical scavenging activity and western blot analysis of stomach tissue from pylorus ligatures rats were also carried out. HPTLC analysis was done to understand the phyto-pharmacological relationship. Results: Methanol extract at a dose level of 100 mg/kg and 200 mg/kg body weight showed 72 and 78 % ulcer protection when compared to negative control whereas reference drug shown 82 % protection in Indomethacin-pylorus ligation model. Further, methanol extract also showed protective effect against 70 % v/v ethanol and stress induced gastric ulcer model. About 84 % protection as compared to cimetidine (85 %) was seen in western blot analysis of stomach tissue from pylorus ligatures rats. HPTLC analysis of methanol extract of P. foetida L. confirmed the presence of β-sitosterol. In DPPH* radical scavenging activity, the ICtextlessinftextgreater50textless/inftextgreater value was observed to be 43.52 μg/ml. Conclusions: These observations established the traditional claim and thus Paederia foetida could be a potent gastroprotective agent for use in future. The gastroprotective activity might be mediated by the Nrf2 mediated antioxidant and anti secretory effects.
BibTeX:
@article{pop00007,
  author = {Chanda, Silpi and Deb, Lokesh and Tiwari, Raj Kumar and Singh, Kuldeep and Ahmad, Sayeed},
  title = {Gastroprotective mechanism of Paederia foetida Linn. (Rubiaceae) – a popular edible plant used by the tribal community of North-East India},
  journal = {BMC Complementary and Alternative Medicine},
  year = {2015},
  volume = {15},
  number = {1},
  pages = {304},
  url = {http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0831-0},
  doi = {https://doi.org/10.1186/s12906-015-0831-0}
}
Tanwer, N., Kaur, R., Rana, D., Singh, R., Singh, K., Tanwar, N., Rana, D., Kaur, R., Singh, R. and Singh, K. Synthesis and characterization of Pyrazoline derivatives 2015 Journal of Integrated Science and Technology
Vol. 3(2), pp. 39-41 
article URL 
Abstract: In the present study the synthesis of pyrazoline derivatives were carried out by cyclization of the chalchone with hydrazine hydrate in the presence of the formic acid. The synthesized pyrazoline derivatives were synthesized on the basis of prediction of activity spectra for substances (PASS). All the synthesized compounds were characterized by spectral analysis (1H NMR).
BibTeX:
@article{pop00014,
  author = {Tanwer, Naveen and Kaur, Rajneesh and Rana, Devika and Singh, Raman and Singh, Kuldeep and Tanwar, N and Rana, Devika and Kaur, Rajneesh and Singh, Raman and Singh, Kuldeep},
  title = {Synthesis and characterization of Pyrazoline derivatives},
  journal = {Journal of Integrated Science and Technology},
  year = {2015},
  volume = {3},
  number = {2},
  pages = {39--41},
  url = {http://pubs.iscience.in/journal/index.php/jist/article/view/313}
}
Arora, A.K., Jaswal, V.S., Singh, K. and Singh, R. Applications of metal/mixed metal oxides as photocatalyst: A review 2016 Oriental Journal of Chemistry
Vol. 32(4), pp. 2035-2042 
article DOI URL 
Abstract: Metal oxides/ Mixed metal oxides have wide applications as catalyst, Adsorbents, Superconductors, semiconductors, ceramics, antifungal agents and also have spacious applications in medicines. This review article is focused on their applications as photocatalyst in various organic reactions.
BibTeX:
@article{pop00003,
  author = {Arora, Avnish Kumar and Jaswal, Vivek Sheel and Singh, Kuldeep and Singh, Raman},
  title = {Applications of metal/mixed metal oxides as photocatalyst: A review},
  journal = {Oriental Journal of Chemistry},
  year = {2016},
  volume = {32},
  number = {4},
  pages = {2035--2042},
  url = {http://www.orientjchem.org/vol32no4/applications-of-metalmixed-metal-oxides-as-photocatalyst-a-review/},
  doi = {https://doi.org/10.13005/ojc/320430}
}
Kaur, R., Singh, K. and Singh, R. 1,5-benzothiazepine: Bioactivity and targets 2016 Chemical Biology Letters
Vol. 3(1), pp. 18-31 
article URL 
Abstract: 1,5-Benzothiazepine nucleus is present in a number of clinically used drugs such as diltiazem, clentiazem, thiazesim, quetiapine, and clothiapine. 1,5-Benzothiazepine can be easily introduced in the molecule having 2-aminothiophenol moiety. This article considers various targets for 1,5-benzothiazepine nucleus to establish structural activity relationship. It is an attempt to compile account of various structural modification in 1,5-benzothiazepine scaffold as reported for their versatile biological activities. This review would provide a platforms for selection of suitable moieties and development of specific chemical entities with desired features.
BibTeX:
@article{pop00010,
  author = {Kaur, Rajneesh and Singh, Kuldeep and Singh, Raman},
  title = {1,5-benzothiazepine: Bioactivity and targets},
  journal = {Chemical Biology Letters},
  year = {2016},
  volume = {3},
  number = {1},
  pages = {18--31},
  url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/453}
}
Arora, A.K., Jaswal, V.S., Singh, K. and Singh, R. Metal/Mixed Metal Oxides and their Applications as Adsorbents 2016 International Journal of Chemical Sciences
Vol. 14(4), pp. 3215-3227 
article URL 
Abstract: Metal oxides/mixed metal oxides have wide applications as catalyst, adsorbents, superconductors, semiconductors, ceramics, antifungal agents and also have spacious applications in medicines. This review article is focused on their applications as adsorbents in various organic reactions.
BibTeX:
@article{pop00011,
  author = {Arora, Avnish Kumar and Jaswal, V S and Singh, K and Singh, R},
  title = {Metal/Mixed Metal Oxides and their Applications as Adsorbents},
  journal = {International Journal of Chemical Sciences},
  year = {2016},
  volume = {14},
  number = {4},
  pages = {3215--3227},
  url = {https://www.tsijournals.com/articles/metalmixed-metal-oxides-and-their-applications-as-adsorbents.pdf}
}
Arora, A.K., Jaswal, V.S., Singh, K. and Singh, R. Chemical evolution and origin of life: A review 2016 Chemical Biology Letters
Vol. 3(1), pp. 9-17 
article URL 
Abstract: Life has evolved approximately 3.7 billion years ago on Earth while the Earth itself was formed some 4.6 billion years ago. So it was the time of 0.9 billion years in which chemical reactions took place and formation of first living cell occurred. There are various views on origin of life. This review discusses and compares these theories with respect to chemical evolution and origin of life.
BibTeX:
@article{pop00019,
  author = {Arora, Avnish Kumar and Jaswal, Vivek Sheel and Singh, Kuldeep and Singh, Raman},
  title = {Chemical evolution and origin of life: A review},
  journal = {Chemical Biology Letters},
  year = {2016},
  volume = {3},
  number = {1},
  pages = {9--17},
  url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/395}
}
Khare, R. and Singh, K. Proceedings of national conference on recent advances in chemical sciences 2016 Chemistry Department, MMU Mullana  article URL 
BibTeX:
@article{pop00023,
  author = {Khare, Rajshree and Singh, Kuldeep},
  title = {Proceedings of national conference on recent advances in chemical sciences},
  journal = {Chemistry Department, MMU Mullana},
  year = {2016},
  url = {https://books.google.com/books?id=cSKZDQAAQBAJ}
}
Singh, R., Kaur, R. and Singh, K. A review on Synthesis of Aminoacetanilides 2016 Integrated Research Advances
Vol. 3(2), pp. 30-39 
article URL 
Abstract: Aminoacetanilides have many applications in pharmaceutical industry, dyes and pigment industry, and are important intermediates to synthesize various heterocycles and aromatics. This review discusses various synthetic conditions and use of aminoacinalids.
BibTeX:
@article{singh2016i,
  author = {Singh, Raman and Kaur, Rajneesh and Singh, Kuldeep},
  title = {A review on Synthesis of Aminoacetanilides},
  journal = {Integrated Research Advances},
  year = {2016},
  volume = {3},
  number = {2},
  pages = {30--39},
  url = {http://www.pubs.iscience.in/journal/index.php/ira/article/view/471}
}
Chanda, S., Ahmad, S., Singh, K. and Tiwari, R. Targeted Metabolite Analysis of Iridoids of Paederia foetida: A Popular Tribal Edible Plant of Northeast, India 2017 Asian Journal of Chemistry
Vol. 29(8), pp. 1713-1717 
article DOI URL 
Abstract: Paederia foetida L., a wild edible plant used as a vegetable and medicine by the tribal people of India, produces iridoids. Taking into account the health benefits of iridoids, here we proposed a simple, economical, most dependable, moreover practically approachable method for the simultaneous estimation of iridoids from the extract of P. foetida. HPTLC method was developed and validated as per ICH guidelines. The developed HPTLC system includes the separation on pre-coated silica gel 60 F 254 aluminium sheets with a solvent system chloroform, methanol and formic acid in a ratio of 8: 2.5: 0.1 (v/v/v) as mobile phase and quantitative densitometric scan done by absorbance measurement at 245 nm. The system produces compact spots of the asperuloside and paederoside at Rf values of 0.56 and 0.65, respectively. The linearity was found to be in the range of 400-3000 ng/spot for both with respect to peak area. The limits of detection and quantification values were found to be 121.23 and 363.69 ng/spot, respectively for asperuloside and 94.11 and 228.33 ng/spot, respectively for paederoside. Recovery values 98 to 99 % for both the reference standards indicate the excellent accuracy of the method. This method could be recommended as an analytical tool for quantification, quality control and also in herbal formulation which contains iridoids.
BibTeX:
@article{pop00018,
  author = {Chanda, S. and Ahmad, S. and Singh, K. and Tiwari, R.K.},
  title = {Targeted Metabolite Analysis of Iridoids of Paederia foetida: A Popular Tribal Edible Plant of Northeast, India},
  journal = {Asian Journal of Chemistry},
  year = {2017},
  volume = {29},
  number = {8},
  pages = {1713--1717},
  url = {http://www.asianjournalofchemistry.co.in/user/ViewFreeArticle.aspx?ArticleID=29818},
  doi = {https://doi.org/10.14233/ajchem.2017.20585}
}
Kaur, R., Tripathi, D., Singh, K. and Singh, R. Recent advances in β-lactam chemistry 2018 Integrated Research Advances
Vol. 5(2), pp. 52-57 
article URL 
Abstract: Beta-lactams are one of the essential heterocycles which have saved humans from deadly infections. Over the years many methods have been developed. This review classifies various methods based on reagents and reactions. It has been concluded that Ketene−Imine Staudinger Reaction is the method of choice.
BibTeX:
@article{pop00017,
  author = {Kaur, R and Tripathi, D and Singh, K and Singh, R},
  title = {Recent advances in β-lactam chemistry},
  journal = {Integrated Research Advances},
  year = {2018},
  volume = {5},
  number = {2},
  pages = {52--57},
  url = {http://www.pubs.iscience.in/journal/index.php/ira/article/view/849}
}
Singh, R. and Singh, K. Biological patent and patentability 2018 Integrated Journal of Social Sciences
Vol. 5(1), pp. 35-40 
article URL 
Abstract: Development in the field of Biological patent sprouted a new world in biotechnology, which permits scientist to alter natural biological matter for commercial profit. In response to Scientific Breakthrough in biotechnology, the innovative technologies, demand of capitalist market place and patent law has expanded to accommodate a range of biological inventions. There is always a controversial concept and views whether gene patenting have a positive impact upon research and development, health care and the protection of the environment or not. So, the applicability of patent of substance and process of natural origin is always a topic of discussion or debate which may have either of the faces. The scope and reach of biological patents vary among Jurisdictions. Beside all this, this article provides some glimpses of basic Knowledge of biological patents with their need, types and few landmark examples.
BibTeX:
@article{pop00022,
  author = {Singh, Raman and Singh, Kuldeep},
  title = {Biological patent and patentability},
  journal = {Integrated Journal of Social Sciences},
  year = {2018},
  volume = {5},
  number = {1},
  pages = {35--40},
  url = {http://www.pubs.iscience.in/journal/index.php/ijss/article/view/859}
}
Kaur, R., Singh, R., Kumar, A. and Singh, K. Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives 2019 SynOpen
Vol. 03(02), pp. 67-70 
article DOI URL 
Abstract: A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were prepared by using click chemistry.
BibTeX:
@article{Kaur2019,
  author = {Kaur, Rajneesh and Singh, Raman and Kumar, Antresh and Singh, Kuldeep},
  title = {Click Chemistry Approach to Isoindole-1,3-dione Tethered 1,2,3-Triazole Derivatives},
  journal = {SynOpen},
  year = {2019},
  volume = {03},
  number = {02},
  pages = {67--70},
  url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690326},
  doi = {https://doi.org/10.1055/s-0039-1690326}
}
Chanda, S., Tiwari, R.K., Kumar, A. and Singh, K. Nutraceuticals Inspiring the Current Therapy for Lifestyle Diseases 2019 Advances in Pharmacological Sciences
Vol. 2019, pp. 1-5 
article DOI URL 
Abstract: Nutraceuticals are the pharmaceutically blended products that possess both nutritional as well as the medicinal value. Such a product is designed to improve the physical health, fight against day-to-day challenges such as stress, increase longevity, etc. Nowadays, emphasis is given to those herbs which are used as food and medicine due to its greater acceptance. Due to dynamic action, the popularity of nutraceuticals among people as well as healthcare providers has been increased over medicines and health supplements. This review documents herbs with a wide variety of therapeutic values such as immunity booster, antidiabetic, anticancer, antimicrobial, and gastroprotective. These herbs could be better options to formulate as nutraceuticals. Several nutraceuticals are described based on their availability as food, chemical nature, and mechanism of action.
BibTeX:
@article{pop00011,
  author = {Chanda, Silpi and Tiwari, Raj Kumar and Kumar, Arun and Singh, Kuldeep},
  title = {Nutraceuticals Inspiring the Current Therapy for Lifestyle Diseases},
  journal = {Advances in Pharmacological Sciences},
  year = {2019},
  volume = {2019},
  pages = {1--5},
  url = {https://www.hindawi.com/journals/aps/2019/6908716/},
  doi = {https://doi.org/10.1155/2019/6908716}
}
Puthiyaveetil Yoosaf, M.A., Jayaprakash, A., Ghosh, S., Jaswal, V.S., Singh, K., Mandal, S., Shahid, M., Yadav, M., Das, S. and Kumar, P. Zein film functionalized with gold nanoparticles and the factors affecting its mechanical properties 2019 RSC Advances
Vol. 9(43), pp. 25184-25188 
article DOI URL 
Abstract: A green chemical approach to substitute biologically hazardous polymer.
BibTeX:
@article{pop00016,
  author = {Puthiyaveetil Yoosaf, Mohammed Ajmal and Jayaprakash, Anjana and Ghosh, Somnath and Jaswal, Vivek Sheel and Singh, Kuldeep and Mandal, Soumit and Shahid, M. and Yadav, Munendra and Das, Subhojit and Kumar, Pankaj},
  title = {Zein film functionalized with gold nanoparticles and the factors affecting its mechanical properties},
  journal = {RSC Advances},
  year = {2019},
  volume = {9},
  number = {43},
  pages = {25184--25188},
  url = {http://xlink.rsc.org/?DOI=C9RA04527A},
  doi = {https://doi.org/10.1039/C9RA04527A}
}
Singh, K., Kulbir, K., Gupta, T., Kaur, R. and Singh, R. Applications of Rozen's Reagent in Oxygen-Transfer and C-H Activation Reactions 2019 Synthesis (Germany)
Vol. 51(2), pp. 371-383 
article DOI URL 
Abstract: Rozen's reagent (hypofluorous acid-acetonitrile complex, HOFtextperiodcenteredMeCN) is a robust nonspecific oxygen-transfer reagent and became a proven tool for the oxidation of difficult-to-oxidize molecules. It has been applied to instant oxygen transfers to functional groups such as alkenes, alkynes, and aromatic hydrocarbons, epoxidation, oxidation of alcohols, amines, and alkynes, oxygen-transfer reactions with nitrogen, phosphorus, and sulfur-containing substrates, and α-hydroxylation of carbonyl groups. Apart from being a potential green oxidizing agent, the complex has applications in 18 O-labeling and C-H functionalization strategies. Recent uses of Rozen's reagent in developing nanomaterials and oxidized expanded graphite indicate the enormous potential of the reagent. These aspects are discussed in this review. 1 Introduction 2 Synthesis and Physical Properties 3 Safety and Handling 4 Oxygen-Transfer Reactions 4.1 General Mechanism of Oxygen Transfer 4.2 Epoxidation 4.3 Oxidation of Alkynes 4.4 Oxidation of Aromatic Alcohols and Phenols 4.5 Oxidation of Nitrogen-Containing Compounds 4.6 Conversion of Aldehydes into Nitriles 4.7 Oxidation of Alcohols and Ethers 4.8 Oxidation of Sulfur-Containing Compounds 4.9 Oxygen-Transfer Reaction with Phosphine, Phosphite, and Phosphinite Compounds 5 C-H Activation Reactions 5.1 Hydroxylation of Nonactivated Tertiary Saturated Carbon Center 5.2 Hydroxylation of Aromatic Carbon Center 5.3 α-Hydroxylation of Carbonyl Group 5.4 Activation of α-Hydrogens of α-Amino Acids 6 Other Uses 7 Green Chemistry and Rozen's Reagent 8 Experimental Problems 9 Further Applications 10 Conclusions.
BibTeX:
@article{pop00021,
  author = {Singh, Kuldeep and Kulbir, Kulbir and Gupta, Tarang and Kaur, Rajneesh and Singh, Raman},
  title = {Applications of Rozen's Reagent in Oxygen-Transfer and C-H Activation Reactions},
  journal = {Synthesis (Germany)},
  year = {2019},
  volume = {51},
  number = {2},
  pages = {371--383},
  url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1609638},
  doi = {https://doi.org/10.1055/s-0037-1609638}
}
Singh, K., Kaur, R. and Singh, R. SYNTHESIS OF 1,2,3-TRIAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF 2020
Vol. 2018(September), pp. 92027School: Maharishi Markandeshwar No (Deemed to be University) Mullana, (32) Priority Haryana - 133207 Haryana India 
misc  
BibTeX:
@misc{IPO2018,
  author = {Singh, Kuldeep and Kaur, Rajneesh and Singh, Raman},
  title = {SYNTHESIS OF 1,2,3-TRIAZOLE CARBOXAMIDES AND DERIVATIVES THEREOF},
  publisher = {IPO},
  school = {Maharishi Markandeshwar No (Deemed to be University) Mullana, (32) Priority Haryana - 133207 Haryana India},
  year = {2020},
  volume = {2018},
  number = {September},
  pages = {92027}
}
Kaur, R., Singh, R., Kumar, A., Kaur, S., Priyadarshi, N., Singhal, N.K. and Singh, K. 1,2,3-Triazole β-lactam conjugates as antimicrobial agents 2020 Heliyon
Vol. 6(6), pp. e04241 
article DOI URL 
Abstract: A convenient and efficient synthesis of new triazole β-lactam conjugates using click chemistry is described. β-lactam 15 and 16 were prepared using cycloaddition strategy and propargylated at N-1 to afford compounds 17 and 18. Cu-catalyzed click reaction of these β-lactams 17 and 18 with different aryl azides provided 1,2,3-triazole conjugates 6 and 7, respectively. The products were fully characterized spectroscopically and tested against Gram-(+) and Gram-(-) bacteria. Compound 7a and 7c were found to be most active.
BibTeX:
@article{Kaur2020,
  author = {Kaur, Rajneesh and Singh, Raman and Kumar, Antresh and Kaur, Satvinder and Priyadarshi, Nitesh and Singhal, Nitin Kumar and Singh, Kuldeep},
  title = {1,2,3-Triazole β-lactam conjugates as antimicrobial agents},
  journal = {Heliyon},
  year = {2020},
  volume = {6},
  number = {6},
  pages = {e04241},
  url = {https://linkinghub.elsevier.com/retrieve/pii/S2405844020310859 https://doi.org/10.1016/j.heliyon.2020.e04241},
  doi = {https://doi.org/10.1016/j.heliyon.2020.e04241}
}
Singh, R., Singh, K., Pundhir, P. and Kaushik, P. MCQs ON CORONAVIRUSES for various competitive examinations 2020 https://play.google.com/store/books/details?id=K-z5DwAAQBAJ
Vol. 1, pp. 77 
article URL 
BibTeX:
@article{pop00003,
  author = {Singh, R and Singh, K and Pundhir, P and Kaushik, P},
  title = {MCQs ON CORONAVIRUSES for various competitive examinations},
  journal = {https://play.google.com/store/books/details?id=K-z5DwAAQBAJ},
  year = {2020},
  volume = {1},
  pages = {77},
  url = {https://books.google.com/books?hl=en&lr=&id=K-z5DwAAQBAJ&oi=fnd&pg=PA2&dq=(%22Hand+washing%22+OR+%22Hand+disinfection%22+OR+%22Hand+sanitizing%22)+AND+(%22COVID-19%22+OR+%22SARS-CoV-2%22)+AND+(Dermatitis+OR+Eczema+OR+%22skin+reaction%22)&ots=11mUgQplog&si}
}
Kaur, R., Singh, R., Ahlawat, P., Kaushik, P. and Singh, K. Contemporary advances in therapeutic portfolio of 2-Azetidinones 2020 Chemical Biology Letters
Vol. 7(1), pp. 13-26 
article URL 
Abstract: The heterocycle moieties form the site of reaction in many enzymes and co-enzymes and also act as an important pharmacophore in the pharmaceutical drug designs. 2-Azetidinones are the 2-carbonyl derivatives of azetidine, more commonly known as β-lactams. These structural entities occupied a central role in the vigil against bacterial infections over the past few decades. A subclass of these heterocyclic systems, monobactams or monocyclic β-lactam derivatives exhibits several biological activities including antibacterial, antifungal, antiprotozoal, anti-mycobacterial, anti-HIV, antiviral, antimalarial, antioxidant, apoptotic inhibitors, anti-inflammatory activity, anticancer activity, herbicidal activity, etc. Monobactams has resistant to the β-lactamase enzyme and could be a reasonable starting point for developing new drugs or inhibitors. In the present review, pharmacological activities of monocyclic β-lactam derivatives have been discussed with respect to current research in the structure-activity relationships in different therapeutic areas.
BibTeX:
@article{pop00020,
  author = {Kaur, Rajneesh and Singh, Raman and Ahlawat, Priyanka and Kaushik, Parul and Singh, Kuldeep},
  title = {Contemporary advances in therapeutic portfolio of 2-Azetidinones},
  journal = {Chemical Biology Letters},
  year = {2020},
  volume = {7},
  number = {1},
  pages = {13--26},
  url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/987}
}
Porwal, J., Porwal, S.K., Singh, R. and Singh, K. Climate Change, Photosynthesis and Advanced Biofuels 2020 Climate Change, Photosynthesis and Advanced Biofuels  book DOI URL 
Abstract: 4. Jyoti Porwal, Suheel K. Porwal, Raman Singh, Kuldeep Singh Synthetic Biofuels and Green-House Gas Mitigation in Climate Change, Photosynthesis and Advanced Biofuels: Role of Biotechnology in Production of Value-added Plant Bio-products Eds. Ashwani Kumar, Yuan-Yeu Yau, Shinjiro Ogita & Renate Scheibe , Springer 2020
BibTeX:
@book{Porwal2020,
  author = {Porwal, Jyoti and Porwal, Suheel K. and Singh, Raman and Singh, Kuldeep},
  title = {Climate Change, Photosynthesis and Advanced Biofuels},
  booktitle = {Climate Change, Photosynthesis and Advanced Biofuels},
  publisher = {Springer Singapore},
  year = {2020},
  edition = {2020},
  url = {http://link.springer.com/10.1007/978-981-15-5228-1},
  doi = {https://doi.org/10.1007/978-981-15-5228-1}
}
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