@article{pop00001, abstract = {The most stable is not necessarily the most easy to obtain! Two new stable crystal forms of the 120 year old compound sym-trinitrobenzene are reported. These elusive forms have been obtained by the use of an additive, trisindane, that can act as a mimic in the crystallization experiment (see scheme).}, annote = {Query date: 2020-06-14 18:25:01}, author = {Thallapally, Praveen K. and Jetti, Ram K. R. and Katz, Amy K. and Carrell, H. L. and Singh, Kuldeep and Lahiri, Kakali and Kotha, Sambasivarao and Boese, Roland and Desiraju, Gautam R.}, doi = {10.1002/anie.200352253}, issn = {1433-7851}, journal = {Angewandte Chemie International Edition}, keywords = {Additives,Crystal growth,Inhibition,Polymorphism}, month = {feb}, number = {9}, pages = {1149–1155}, title = polymorphism_of_1_3_5-trinitrobenzene_induced_by_a_trisindane_additive, type = {Journal article}, url = {http://doi.wiley.com/10.1002/anie.200352253}, volume = {43}, year = {2004} } @article{Kotha2004, abstract = {An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs 2CO 3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields. An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs 2CO 3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields. {\textcopyright} 2004 Published by Elsevier Ltd.}, author = {Kotha, Sambasivarao and Singh, Kuldeep}, doi = {10.1016/j.tetlet.2004.11.013}, isbn = {0040-4039}, issn = {00404039}, journal = {Tetrahedron Letters}, keywords = {Constrained amino acid derivatives,Diethyl acetamidomalonate,Heterocycles,Metathesis,Regioselective N-alkylation}, month = {dec}, number = {52}, pages = {9607–9610}, publisher = {Elsevier}, title = synthesis_of_constrained_amino_acid_derivatives_by_ring-closing_metathesis, url = {https://linkinghub.elsevier.com/retrieve/pii/S0040403904024487}, volume = {45}, year = {2004} } @article{Kotha2007, abstract = {Suitably functionalized glycine derivatives undergo a cross-enyne and ring-closing metathesis cascade to generate macroheterocyclic ring systems in good yield. These macrocycles, prepared on the basis of a fragment coupling strategy, consist of 13-16-membered rings. To this end, 1,5-hexadiene was found to be a promising cross-coupling partner to generate macrocycles by this tandem metathesis sequence. {\textcopyright} Wiley-VCH Verlag GmbH {\&} Co. KGaA, 2007.}, author = {Kotha, Sambasivarao and Singh, Kuldeep}, doi = {10.1002/ejoc.200700744}, issn = {1434193X}, journal = {European Journal of Organic Chemistry}, keywords = {Amino acids,Heterocycles,Macrocycles,Metathesis,Ring-closing metathesis,Tandem reactions}, month = {dec}, number = {35}, pages = {5909–5916}, title = a_building-block_approach_suitable_for_diversity-oriented_synthesis_of_densely_functionalized_macroheterocycles_with_amino_acid_scaffolds, url = {http://doi.wiley.com/10.1002/ejoc.200700744}, volume = {2007}, year = {2007} } @article{pop00008, abstract = {Highly functionalized cage compounds have been prepared via cross-metathesis (CM) using Grubbs modified N-tolyl catalyst 7. A strategic utilization of photo-thermal metathesis and catalytic metathesis sequence for the synthesis of functionalized caged molecules has been demonstrated. {\textcopyright} 2010 Elsevier Ltd. All rights reserved.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Kotha, Sambasivarao and Seema, Vittal and Singh, Kuldeep and Deodhar, Kodand Dinkar}, doi = {10.1016/j.tetlet.2010.02.131}, issn = {00404039}, journal = {Tetrahedron Letters}, month = {apr}, number = {17}, pages = {2301–2304}, title = strategic_utilization_of_catalytic_metathesis_and_photo-thermal_metathesis_in_caged_polycyclic_frames, type = {Journal article}, url = {https://linkinghub.elsevier.com/retrieve/pii/S0040403910003424}, volume = {51}, year = {2010} } @article{pop00005, abstract = {A simple methodology to a unique macrocyclic $\alpha$-amino acid (AAA) derivative involving three step synthetic sequence has been reported. In addition, various ruthenium based catalysts were studied to enhance the selectivity of the desired macrocyclic AAA derivative 6. The fluorescence behavior of these AAA derivatives 5 and 6 indicate their potential applications in biological sciences as biomarkers, ion sensors and peptidomimetics. {\textcopyright} 2010 Elsevier B.V. All rights reserved.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Kotha, Sambasivarao and Bansal, Deepti and Singh, Kuldeep and Banerjee, Subhasree}, doi = {10.1016/j.jorganchem.2011.02.019}, issn = {0022328X}, journal = {Journal of Organometallic Chemistry}, keywords = {Fluorescent $\alpha$-amino acid (AAA) derivatives,Macrocyclic $\alpha$-amino acid,Ruthenium based catalysts,Tandem metathesis}, month = {may}, number = {9}, pages = {1856–1860}, title = ring-closing_metathesis_cascade_catalyzed_by_ruthenium_based_catalysts, type = {Journal article}, url = {https://linkinghub.elsevier.com/retrieve/pii/S0022328X1100132X}, volume = {696}, year = {2011} } @article{pop00006, abstract = {The northeastern region of India constitutes one of the biodiversity hotspots of the world. The ethnic groups inhabiting this region practice their distinctive traditional knowledge systems using biodiversity for food, shelter and healthcare. Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. Many of its therapeutic properties relate to the gastrointestinal system and suggest its potential utility for gastrointestinal ailments. This is a review of the ethnobotanical uses, phytochemistry and therapeutic properties of P. foetida compiled from various reports. P. foetida is promising as a remedy for life-style related conditions, especially treatment of ulcers. Its utility highlights the need for proper evaluation of tribal plants as medicines and the species could be considered for development of new drugs. {\textcopyright} 2013 Northeast Forestry University and Springer-Verlag Berlin Heidelberg.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Chanda, Silpi and Sarethy, Indira P. and De, Biplab and Singh, Kuldeep}, doi = {10.1007/s11676-013-0369-2}, issn = {1007-662X}, journal = {Journal of Forestry Research}, keywords = {Paederia foetida,Tribal medicine,ethnobotany,phytochemistry,therapeutic,ulcer}, month = {dec}, number = {4}, pages = {801–808}, title = paederia_foetida_a_promising_ethno-medicinal_tribal_plant_of_northeastern_india, type = {Journal article}, url = {http://link.springer.com/10.1007/s11676-013-0369-2}, volume = {24}, year = {2013} } @article{pop00012, abstract = {Treatment failure is a major cause of concern for the Helicobacter pylorirelated gastroduodenal diseases like gastritis, peptic ulcer and gastric cancer. The antibacterial activity of Paederiafoetidaagainst few clinical isolates of H.pyloriin vitro was evaluated. The methanolicleaf extractshowing its effectiveness in inhibiting in vitroH. pylori growth irrespective of the genetic makeup of the strains. This study provides novel insights into the therapeutic effect of P. foetidaagainst H. pylori infection, suggesting its potential as an alternative therapy, and opens the way for further studies on identification of novel antimicrobial targets of P. foetida.}, annote = {Query date: 2020-06-14 18:25:01}, author = silpi_chanda_valentina_gehlot_rajashree_das_shweta_mahant_k_unal_das_kuldeep_singh_sayeed_ahmad_and_chanda_s_and_gehlot_v_and_das_r_and_mahant_s_and_das_k_and_singh_k_and_ahmad_s_journal_world_journal_of_pharmaceutical_research_keywords_helicobacter_pylori_paederia_foetida._number_4_pages_1234--1243_title_antimicrobial_activity_of_herbal_extract_against_drug_resistant_h._pylori_isolates_from_india, type = {Journal article}, url = {http://www.wjpr.net/dashboard/abstract{\_}id/1017}, volume = {3}, year = {2014} } @article{pop00013, abstract = {The aim of this study was to investigate the antioxidant activity of different fractionated extracts of leaves of Paederia foetida by DPPH* scavenging assay and phytochemical analysis of the methanolic extract of the leaf. Materials and Methods: The fresh leaves of P. foetida was extracted by using methanol and then proceed for solvent fractionation. The extract was tested for phytochemical analysis and antioxidant activity using DPPH* scavenging assay. Results: Methanolic extract showed the presence of triterpenoids, volatile oil, sterols, alkaloid and glycoside. The yield of methanolic extract was 36{\%}w/w which showed the highest antioxidant activity as compared to other fractions. Conclusion: Paederia foetida leaf extracts possessed free radical scavenging activity. {\textcopyright} 2014 By IYPF All rights reserved.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Chanda, Silpi and Ahmad, Sayeed and Singh, Kuldeep}, issn = {09759344}, journal = {International Journal of Drug Development and Research}, keywords = {Antioxidant,DPPH,Paederia foetida}, number = {2}, pages = {105–109}, title = comparison_of_in_vitro_antioxidant_potential_of_fractioned_paederia_foetida_leaf_extract, type = {Journal article}, url = {https://www.ijddr.in/drug-development/comparison-of-in-vitro-antioxidant-potential-of-fractioned-paederiafoetida-leaf-extract.php?aid=5515}, volume = {6}, year = {2014} } @article{pop00007, abstract = {Background: The objective of the present study is to evaluate the gastroprotective activity of Paederia foetida L. leaf for gastric ulcer. Methods: The methanol extract of P. foetida L. leaves at two different dose levels was investigated for gastroprotective potential by using Indomethacin-pylorus ligation, alcohol induced and water immersion stress induced model in rats. In vitro DPPH* radical scavenging activity and western blot analysis of stomach tissue from pylorus ligatures rats were also carried out. HPTLC analysis was done to understand the phyto-pharmacological relationship. Results: Methanol extract at a dose level of 100 mg/kg and 200 mg/kg body weight showed 72 and 78 {\%} ulcer protection when compared to negative control whereas reference drug shown 82 {\%} protection in Indomethacin-pylorus ligation model. Further, methanol extract also showed protective effect against 70 {\%} v/v ethanol and stress induced gastric ulcer model. About 84 {\%} protection as compared to cimetidine (85 {\%}) was seen in western blot analysis of stomach tissue from pylorus ligatures rats. HPTLC analysis of methanol extract of P. foetida L. confirmed the presence of $\beta$-sitosterol. In DPPH* radical scavenging activity, the IC{\textless}inf{\textgreater}50{\textless}/inf{\textgreater} value was observed to be 43.52 $\mu$g/ml. Conclusions: These observations established the traditional claim and thus Paederia foetida could be a potent gastroprotective agent for use in future. The gastroprotective activity might be mediated by the Nrf2 mediated antioxidant and anti secretory effects.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Chanda, Silpi and Deb, Lokesh and Tiwari, Raj Kumar and Singh, Kuldeep and Ahmad, Sayeed}, doi = {10.1186/s12906-015-0831-0}, issn = {1472-6882}, journal = {BMC Complementary and Alternative Medicine}, keywords = {Antioxidant,Gastroprotective,North-East India,Paederia foetida}, month = {dec}, number = {1}, pages = {304}, title = gastroprotective_mechanism_of_paederia_foetida_linn._rubiaceae_a_popular_edible_plant_used_by_the_tribal_community_of_north-east_india, type = {Journal article}, url = {http://bmccomplementalternmed.biomedcentral.com/articles/10.1186/s12906-015-0831-0}, volume = {15}, year = {2015} } @article{pop00014, abstract = {In the present study the synthesis of pyrazoline derivatives were carried out by cyclization of the chalchone with hydrazine hydrate in the presence of the formic acid. The synthesized pyrazoline derivatives were synthesized on the basis of prediction of activity spectra for substances (PASS). All the synthesized compounds were characterized by spectral analysis (1H NMR).}, annote = {Query date: 2020-06-14 18:25:01}, author = {Tanwer, Naveen and Kaur, Rajneesh and Rana, Devika and Singh, Raman and Singh, Kuldeep}, journal = {Journal of Integrated Science and Technology}, keywords = {analgesic,anti-inflammatory,antipyretic,chalcone,pyrazole}, pages = {39–41}, title = synthesis_and_characterization_of_pyrazoline_derivatives, type = {Journal article}, url = {http://pubs.iscience.in/journal/index.php/jist/article/view/313}, volume = {3}, year = {2015} } @article{pop00019, abstract = {Life has evolved approximately 3.7 billion years ago on Earth while the Earth itself was formed some 4.6 billion years ago. So it was the time of 0.9 billion years in which chemical reactions took place and formation of first living cell occurred. There are various views on origin of life. This review discusses and compares these theories with respect to chemical evolution and origin of life.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Arora, Avnish Kumar and Jaswal, Vivek Sheel and Singh, Kuldeep and Singh, Raman}, issn = {23479825}, journal = {Chemical Biology Letters}, keywords = {Chemical evolution,Clay,Cyano complexes,Metal oxides,Origin of life}, number = {1}, pages = {9–17}, title = a_review, type = {Journal article}, url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/395}, volume = {3}, year = {2016} } @article{pop00010, abstract = {1,5-Benzothiazepine nucleus is present in a number of clinically used drugs such as diltiazem, clentiazem, thiazesim, quetiapine, and clothiapine. 1,5-Benzothiazepine can be easily introduced in the molecule having 2-aminothiophenol moiety. This article considers various targets for 1,5-benzothiazepine nucleus to establish structural activity relationship. It is an attempt to compile account of various structural modification in 1,5-benzothiazepine scaffold as reported for their versatile biological activities. This review would provide a platforms for selection of suitable moieties and development of specific chemical entities with desired features.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Kaur, Rajneesh and Singh, Kuldeep and Singh, Raman}, issn = {23479825}, journal = {Chemical Biology Letters}, keywords = {1,5-benzothiazepine,Anticholinesterase inhibitor,Antiplatelet aggregation,Glycogen synthase kinase-3$\beta$ inhibitors,Mitogen-activated protein kinase protein inhibitor,Vasodilator}, number = {1}, pages = {18–31}, title = bioactivity_and_targets, type = {Journal article}, url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/453}, volume = {3}, year = {2016} } @article{pop00023, annote = {Query date: 2020-06-14 18:25:01}, author = {Khare, Rajshree and Singh, Kuldeep}, isbn = {9789352673612}, journal = {Chemistry Department, MMU Mullana}, title = proceedings_of_national_conference_on_recent_advances_in_chemical_sciences, url = {https://books.google.co.in/books/about/Proceedings{\_}of{\_}National{\_}Conference{\_}on{\_}Re.html?id=cSKZDQAAQBAJ{\&}redir{\_}esc=y}, year = {2016} } @article{pop00003, abstract = {Metal oxides/ Mixed metal oxides have wide applications as catalyst, Adsorbents, Superconductors, semiconductors, ceramics, antifungal agents and also have spacious applications in medicines. This review article is focused on their applications as photocatalyst in various organic reactions.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Arora, Avnish and Jaswal, Vivek and Singh, Kuldeep and Singh, Raman}, doi = {10.13005/ojc/320430}, file = {:D$\backslash$:/office keygen/Mendeley{\_}rkaur/2016 - Applications of metalmixed metal oxides as photocatalyst A review.pdf:pdf}, issn = {0970020X}, journal = {Oriental Journal of Chemistry}, keywords = {Ceramics,Metal oxides,Mixed metal oxides,Organic reaction}, month = {aug}, number = {4}, pages = {2035–2042}, title = a_review, type = {Journal article}, url = {http://www.orientjchem.org/vol32no4/applications-of-metalmixed-metal-oxides-as-photocatalyst-a-review/}, volume = {32}, year = {2016} } @article{Arora2016, abstract = {Metal oxides/mixed metal oxides have wide applications as catalyst, adsorbents, superconductors, semiconductors, ceramics, antifungal agents and also have spacious applications in medicines. This review article is focused on their applications as adsorbents in various organic reactions.}, author = {Arora, Avnish Kumar}, file = {:D$\backslash$:/office keygen/Mendeley{\_}rkaur/2016 - METALMIXED METAL OXIDES AND THEIR APPLICATIONS AS ADSORBENTS A Review.pdf:pdf}, issn = {0972-768X}, journal = {Int. J. Chem. Sci.}, keywords = {adsorbent,metal,metal oxide}, number = {4}, pages = {3215–3227}, title = a_review, url = {https://www.tsijournals.com/articles/metalmixed-metal-oxides-and-their-applications-as-adsorbents.pdf}, volume = {14}, year = {2016} } @article{Singh2016, abstract = {Aminoacetanilides have many applications in pharmaceutical industry, dyes and pigment industry, and are important intermediates to synthesize various heterocycles and aromatics. This review discusses various synthetic conditions and use of aminoacinalids.}, author = {Singh, Raman and Kaur, Rajneesh and Singh, Kuldeep}, journal = {Integrated Research Advances}, keywords = {2456-334X,Acylation,Aminoacetanilides}, mendeley-tags = {2456-334X}, month = {sep}, number = {2}, pages = {30–39}, title = a_review_on_synthesis_of_aminoacetanilides, url = {http://www.pubs.iscience.in/journal/index.php/ira/article/view/471}, volume = {3}, year = {2016} } @article{pop00018, abstract = {Paederia foetida L., a wild edible plant used as a vegetable and medicine by the tribal people of India, produces iridoids. Taking into account the health benefits of iridoids, here we proposed a simple, economical, most dependable, moreover practically approachable method for the simultaneous estimation of iridoids from the extract of P. foetida. HPTLC method was developed and validated as per ICH guidelines. The developed HPTLC system includes the separation on pre-coated silica gel 60 F 254 aluminium sheets with a solvent system chloroform, methanol and formic acid in a ratio of 8: 2.5: 0.1 (v/v/v) as mobile phase and quantitative densitometric scan done by absorbance measurement at 245 nm. The system produces compact spots of the asperuloside and paederoside at Rf values of 0.56 and 0.65, respectively. The linearity was found to be in the range of 400-3000 ng/spot for both with respect to peak area. The limits of detection and quantification values were found to be 121.23 and 363.69 ng/spot, respectively for asperuloside and 94.11 and 228.33 ng/spot, respectively for paederoside. Recovery values 98 to 99 {\%} for both the reference standards indicate the excellent accuracy of the method. This method could be recommended as an analytical tool for quantification, quality control and also in herbal formulation which contains iridoids.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Chanda, S. and Ahmad, S. and Singh, K. and Tiwari, R.K.}, doi = {10.14233/ajchem.2017.20585}, issn = {09707077}, journal = {Asian Journal of Chemistry}, keywords = {Asperuloside,Densitometry,Iridoids,Paederia foetida,Paederoside}, number = {8}, pages = {1713–1717}, title = a_popular_tribal_edible_plant_of_northeast_india, type = {Journal article}, url = {http://www.asianjournalofchemistry.co.in/user/ViewFreeArticle.aspx?ArticleID=29{\_}8{\_}18}, volume = {29}, year = {2017} } @article{pop00022, abstract = {Development in the field of Biological patent sprouted a new world in biotechnology, which permits scientist to alter natural biological matter for commercial profit. In response to Scientific Breakthrough in biotechnology, the innovative technologies, demand of capitalist market place and patent law has expanded to accommodate a range of biological inventions. There is always a controversial concept and views whether gene patenting have a positive impact upon research and development, health care and the protection of the environment or not. So, the applicability of patent of substance and process of natural origin is always a topic of discussion or debate which may have either of the faces. The scope and reach of biological patents vary among Jurisdictions. Beside all this, this article provides some glimpses of basic Knowledge of biological patents with their need, types and few landmark examples.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Singh, Raman and Singh, Kuldeep}, journal = {Integrated Journal of Social Sciences}, keywords = {Biological Patent,Development,Need,Scope,types patentability}, mendeley-tags = {Biological Patent,Development,Need,Scope,types patentability}, number = {1}, pages = {35–40}, title = biological_patent_and_patentability, type = {Journal article}, url = {http://www.pubs.iscience.in/journal/index.php/ijss/article/view/859}, volume = {5}, year = {2018} } @article{pop00017, abstract = {Beta-lactams are one of the essential heterocycles which have saved humans from deadly infections. Over the years many methods have been developed. This review classifies various methods based on reagents and reactions. It has been concluded that Ketene−Imine Staudinger Reaction is the method of choice.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Kaur, R and Tripathi, D and Singh, K and Singh, R}, journal = {Integrated Research Advances}, keywords = {Antibacterial,Beta-lactam,antibacterial activity,antibacterial resistance,azomethine linkage}, mendeley-tags = {Beta-lactam,Antibacterial,azomethine linkage,antibacterial activity,antibacterial resistance}, number = {2}, pages = {52–57}, title = recent_advances_in_beta_-lactam_chemistry, type = {Journal article}, url = {http://www.pubs.iscience.in/journal/index.php/ira/article/view/849}, volume = {5}, year = {2018} } @article{pop00015, abstract = {In this article, we report a simple method to synthesize biodegradable zein films functionalized with gold nanoparticles (AuNPs) with significantly improved mechanical properties, as an environmentally benign substitute to biologically hazardous polymers. Zein-coated AuNPs were synthesized using the zein protein as a reducing agent and characterized with IR, UV, CD, $\zeta$-potential, and TEM measurements. The zein protein interaction with the negatively charged surface of AuNPs provides excellent strength to the zein thin film. For the first time, FT-IR spectral studies suggested the strong interaction between AuNPs and zein protein, which was further supported by the higher binding constant (Kb) value. The films were characterized for mechanical properties with spectroscopic and physical experimental investigations. The surface morphology of AuNP-doped zein film was explored by AFM and SEM, which suggested that the AuNPs prevent the buckling of zein film and increase the strength as well as flexibility of the film.}, annote = {Query date: 2020-06-14 18:25:01}, author = c9ra04527a_issn_20462069_journal_rsc_advances_number_43_pages_25184--25188_title_zein_film_functionalized_with_gold_nanoparticles_and_the_factors_affecting_its_mechanical_properties, type = {Journal article}, url = {http://xlink.rsc.org/?DOI=C9RA04527A}, volume = {9}, year = {2019} } @article{pop00021, abstract = {Rozen's reagent (hypofluorous acid–acetonitrile complex, HOF{\textperiodcentered}MeCN) is a robust nonspecific oxygen-transfer reagent and became a proven tool for the oxidation of difficult-to-oxidize molecules. It has been applied to instant oxygen transfers to functional groups such as alkenes, alkynes, and aromatic hydrocarbons, epoxidation, oxidation of alcohols, amines, and alkynes, oxygen-transfer reactions with nitrogen, phosphorus, and sulfur-containing substrates, and $\alpha$-hydroxylation of carbonyl groups. Apart from being a potential green oxidizing agent, the complex has applications in 18O-labeling and C–H functionalization strategies. Recent uses of Rozen's reagent in developing nanomaterials and oxidized expanded graphite indicate the enormous potential of the reagent. These aspects are discussed in this review.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Singh, Kuldeep and Kulbir, Kulbir and Gupta, Tarang and Kaur, Rajneesh and Singh, Raman}, doi = {10.1055/s-0037-1609638}, issn = {0039-7881}, journal = {Synthesis}, keywords = {18 O labeling,C-H functionalization,Rozen oxidation,Rozen's reagent,green synthesis,hypofluorous acid-acetonitrile complex,oxygen-transfer reaction}, month = {jan}, number = {02}, pages = {371–383}, title = applications_of_rozen_s_reagent_in_oxygen-transfer_and_c_h_activation_reactions, type = {Journal article}, url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1609638}, volume = {51}, year = {2019} } @article{pop00011, abstract = {Nutraceuticals are the pharmaceutically blended products that possess both nutritional as well as the medicinal value. Such a product is designed to improve the physical health, fight against day-to-day challenges such as stress, increase longevity, etc. Nowadays, emphasis is given to those herbs which are used as food and medicine due to its greater acceptance. Due to dynamic action, the popularity of nutraceuticals among people as well as healthcare providers has been increased over medicines and health supplements. This review documents herbs with a wide variety of therapeutic values such as immunity booster, antidiabetic, anticancer, antimicrobial, and gastroprotective. These herbs could be better options to formulate as nutraceuticals. Several nutraceuticals are described based on their availability as food, chemical nature, and mechanism of action.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Chanda, Silpi and Tiwari, Raj Kumar and Kumar, Arun and Singh, Kuldeep}, doi = {10.1155/2019/6908716}, issn = {1687-6334}, journal = {Advances in Pharmacological Sciences}, month = {jan}, pages = {1–5}, title = nutraceuticals_inspiring_the_current_therapy_for_lifestyle_diseases, url = {https://www.hindawi.com/journals/aps/2019/6908716/}, volume = {2019}, year = {2019} } @article{Kaur2019, abstract = {A convenient and efficient approach for the synthesis of novel 1,2,3-triazole tethered isoindol-1,3-dione conjugates by a nucleophilic substitution reaction of phthalic anhydride with 1,2,3-triazole containing carbohydrazide is described. The latter were prepared by using click chemistry.}, author = {Kaur, Rajneesh and Singh, Raman and Kumar, Antresh and Singh, Kuldeep}, doi = {10.1055/s-0039-1690326}, issn = {2509-9396}, journal = {SynOpen}, month = {apr}, number = {02}, pages = {67–70}, title = click_chemistry_approach_to_isoindole-1_3-dione_tethered_1_2_3-triazole_derivatives, url = {http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690326}, volume = {03}, year = {2019} } @article{pop00020, abstract = {The heterocycle moieties form the site of reaction in many enzymes and co-enzymes and also act as an important pharmacophore in the pharmaceutical drug designs. 2-Azetidinones are the 2-carbonyl derivatives of azetidine, more commonly known as $\beta$-lactams. These structural entities occupied a central role in the vigil against bacterial infections over the past few decades. A subclass of these heterocyclic systems, monobactams or monocyclic $\beta$-lactam derivatives exhibits several biological activities including antibacterial, antifungal, antiprotozoal, anti-mycobacterial, anti-HIV, antiviral, antimalarial, antioxidant, apoptotic inhibitors, anti-inflammatory activity, anticancer activity, herbicidal activity, etc. Monobactams has resistant to the $\beta$-lactamase enzyme and could be a reasonable starting point for developing new drugs or inhibitors. In the present review, pharmacological activities of monocyclic $\beta$-lactam derivatives have been discussed with respect to current research in the structure-activity relationships in different therapeutic areas.}, annote = {Query date: 2020-06-14 18:25:01}, author = {Kaur, Rajneesh and Singh, Raman and Ahlawat, Priyanka and Kaushik, Parul and Singh, Kuldeep}, journal = {Chemical Biology Letters}, keywords = {antimicrobial,biological activity,drug resistance,monobactam,multi target drugs}, mendeley-tags = {antimicrobial,biological activity,drug resistance,monobactam,multi target drugs}, number = {1}, pages = {13–26}, title = contemporary_advances_in_therapeutic_portfolio_of_2-azetidinones, type = {Journal article}, url = {http://www.pubs.iscience.in/journal/index.php/cbl/article/view/987}, volume = {7}, year = {2020} }

Powered by ComboStrap